Saturday, April 29, 2017

TUBERCULOSIS in India





India’s  TB  Time  Bomb

For the latest writing on this subject, click on :  https://drtramaprasad.blogspot.com/2023/01/world-tb-day-2026.html
                    



Dr. T. Rama Prasad    .......        March, 2020







          March 24, 2020 is 'World TB Day'.


          Robert Koch, a German scientist announced discovery of the bacillus that causes tuberculosis (TB) on March 24, 1882. He must be turning in his grave at our failure to contain TB even after such a long time after his discovery. A day may come when we may not have any drugs to treat MDR-TB & XDR-TB. Given the realities of the scenario, that situation might soon become a frightening reality.

     India is now facing a tuberculosis crisis in terms of morbidity, mortality, magnitude and drug resistance which no earlier generation ever had to face.  There are 2.8 million cases of which  half-a-million may be harbouring drug-resistant bacilli. And 50 crores may be carrying 'latent TB infection'.  Of late, one thousand persons have been dying every day in India due to TB.   And we have been losing 2,240 billion rupees due to TB each year.  Hence, it is imperative that policy makers, politicians in power and the public do some soul searching on the control of TB in India.   Now more than ever, comprehensive and novel methods are to be employed to control TB with the same sincerity and urgency we are witnessing to combat  COVID-19.

TB  Hatao

          If one goes through the 'India TB Report 2018 : Annual Status Report' (https://tbcindia.gov.in/showfile.php?lid=3314),  one gains the impression that there is a committed  political will and a strong programming strategy in place to reach the goal of ending TB in India by 2025,  in line with the 'National Health Policy, 2017'.   Every one concerned should work hard honestly to see that this new initiative would not end as a "TB Hatao" slogan. 

          And to have a critical insight into the conundrum of tuberculosis control in India, read the following.   And read it again in 2025  and on every World TB Day hereafter.


The  PRESENT


          According to the 'Global Report of 2017',  the estimated incidence of TB in India is 2.8 million,  accounting for a quarter of the world's TB cases.   Various new initiatives and policy changes have been made since 2017 for early detection,  better treatment,  more cooperation and positive outcome.   Government of India has set the highly ambitious goal of ending TB in India by 2025,  through 'National Strategic Plan (NSP) 2017 -25', in line with 'National Health Policy 2017'.   This is 5 years ahead of the target of 'Sustainable Development Goals',  and  10 years ahead of the 'End-TB target' of the World Health Organization (WHO). And, according to a recent publication in The Lancet Global Health,  only 57% reduction in incidence and 72% reduction in mortality may be achieved by 2035 with good control measures.  The study projects that eight million persons with TB can be saved over the next 30 years if tests are subsidised and patients are supported to complete the treatment which may cost an extra of 30,300 million rupees.

          In the present set up, with the expressed political will, various new initiatives to facilitate early detection and initiation of cost-free treatment through public health centres and as well through private medical sector are put in place.   Provision of new diagnostic tools like CBNAAT / GeneXpert,  Solid / Liquid Culture DST or Line Probe Assay, and new drugs like Bedaquiline and Delaminid are the additions.   More over, monetary support of Rs.500 per month to the patients during treatment and monetary incentive of Rs.1000 per case to doctors for notifying and giving drugs at the government's cost are being given.   And legally, TB is made a 'notifiable disease'  for better follow up and management.  In addition, pan-India engagement with private sector to close the enormous gaps across the patient-care-cascade in private medical care is initiated through NSP, WJCF, CHAI, CHRI, FIND India, GFATM, CTD, WHO, JEET, etc. to eliminate TB during 2017 - 25.

         We should hope and wish that this strategy would eliminate TB from India by 2025.  The proof of the success may be seen in 2025.   'The proof of the pudding is in the eating'.   Let's review in 2025.   To have a look at the flip side of the coin ('darshan' of the 'avatar' on the reverse), read the following.  And read it in 2025 and on every World TB Day hereafter.


From the PAST  to the  PRESENT


Half a century ago (1967), I entered the campus of a tuberculosis (TB) sanatorium as a medical officer.  It was a sprawling campus of more than 350 acres with serene atmosphere and salubrious climate where about 300 in-patients used to stay.  At that point of time, I thought that the “unfashionable”  TB and the sanatorium would be nonexistent after half a century, with the advent of new drugs. The half a century is now over.  While the sanatorium is fading away,  TB is killing more people than ever before in history  --  1,000 people everyday in India at present !  And, though poverty and TB have a mutually reinforcing relationship,  the wealthy are also affected by TB as the disease spreads through air,  and as even an aristocrat can’t have private air though he may have a private jet aeroplane. Dubbed as “Ebola with wings,”  it flies freely from place to place.  Kamala Nehru, Mohammed Ali Jinnah, Srinivasa Ramanujan, Lennec, Lady Roosevelt, John Keats, Shelly and a host of other celebrities succumbed to TB ! 



     DRUG RESISTANT  TUBERCULOSIS
In those days, words like ‘multi-drug-resistant tuberculosis (MDR-TB)’,  ‘extensively-drug-resistant tuberculosis (XDR-TB)’ and virtually incurable ‘totally-drug-resistant tuberculosis (TDR-TB)’ were not in our parlance.  And, 40 years ago,  I wrote in the columns of The Hindu (Apr. 28, 1977) that" … development of drug resistance, which is a result of inadequate and irregular treatment mostly, has far-reaching implications and if unchecked would make tuberculosis totally unmanageable by the present methods in course of time, whatever be the means. Irregular and inadequate treatment keeps the patient often alive, suffering and infective to disseminate drug-resistant organisms into the environment…. "   Now,  with my experience of half a century in this field, I find that there is less guarantee of a cure now than a few decades ago, notwithstanding the availability of more drugs, due to drug resistance. The ancient disease which is ‘unpopular’ and not ‘sexy’ among the present breed of doctors has become formidable through a metamorphosis due to our misuse of medicines.  There were tools, but we didn’t use them properly.  And so we landed in the medical quagmire.  And now it seems that TB has become insurmountable and invincible,  notwithstanding the introduction of new regimens which include molecules like Bedaquiline, Linezolid and Pretomanid.

GLOBAL  TUBERCULOSIS  REPORTS -- 2016 - 2019 

The magnitude of the problem is underlined by the ‘Global Tuberculosis Report’ released in October 2016.  It stated that India had underestimated TB data between 2000 and 2015.  The present estimates of the report indicate that India has the major burden of having 27 per cent of all the TB cases (10.4 million) in the world (China 14%, Russian Federation 9%), with 2.8 million new and relapse cases,  and more than 4,78,000 deaths (34 per cent of more than 1.5 million deaths worldwide) each year.  And the number of ‘multi-drug-resistant TB’ cases in India in 2018 is a shocking half million (1,30,000 in 2015), topping the world, and ticking the ‘India’s TB Time Bomb’.

Another recently published study (PLOS Medicine, October 25, 2016) found that only 45 per cent of the patients treated at government TB health facilities completed the course of treatment in 2013, and that 61 per cent of them had a relapse of the disease within one year of completion of the treatment                                                                                                                                              1                  (http://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.1002149&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+plosmedicine%2FNewArticles+(PLOS+Medicine+-+New+Articles) !  The actual picture may be worse which may be known to some extent only after the completion of the “National TB Prevalence Survey” scheduled for 2017 – 2018.   No amount of spin and gloss can hide the bitter truth.

IMPERIAL COLLEGE, LONDON STUDY        
                                                                                                                                                                                                                   
A recent (August 25, 2016) study, published in The Lancet Infectious Diseases (www.thelancet.com), by the Imperial College of London, the Government of India’s Revised National TB Control Programme, the World Health Organization (WHO) and some other  organizations(http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_25-8-2016-11-33-10 )  revealed startling information about TB in India.  The study  reveals the disturbing fact that the true total TB burden of India could plausibly be closer to 2.6 to 6.8 million  --  that is 1.2 to 3 times more than the currently believed official estimates of 2.2 million !  It also indicates that over 2 million cases of TB cases were treated (2014) by India’s private sector alone which means that the ‘private bulk’ is of more than 80 per cent of the 2.2 million cases in India.

“WHO”  DISILLUSIONED

Some may think that I have been barking up the wrong tree, but the announcement by the World Health Organization (WHO) in October 2016 to seek a ‘Special United Nations General Assembly (UNGA)’ session on TB vindicates my critical comments.  The WHO seems to be frustrated by the lack of political will to control the deadly TB which has increased by 34 per cent  in India according to the ‘Global TB Report’. The 'Stop TB Partnership' and the WHO will discuss commitments from global heads of State ahead of the 'UN High-Level meeting' on TB in September 2018.  It is time for the alarm to be sounded, when governments cast a blind eye to blatant warning signs.  Some may say that lack of availability of the two new drugs - Bedaquiline and Delaminid - is the cause for increased incidence of drug-resistant TB;  it is like saying that people are dying as there are no ICU units in all the villages !

FAILING   PROGRAMME
Following a good deal of research in India in collaboration with international bodies, domiciliary treatment (treatment at home) came into vogue and we sang the dirge of the TB sanatoriums.  



Authorities publicized that people can easily get rid of TB with just six months treatment at home, fostering undue complacency among the public which did more harm than good.  Often, I ask  the patients, some doctors  and the public ... 'Is it true that TB problem is less, and that it is more easily curable now, compared to earlier decades ?' ... most of them say that it is true.  That is the level of complacency fostered.  Today,  people are more scared of ‘Swine flu’ and ‘Dengue fever’ than TB.  They just don’t know that TB has been killing 1,000 persons every day in India Even the 'tsunami' could kill only 1/20 th (18,000) of the annual toll taken by TB!  And imagine the stupendous economic loss to the country and the families due to the morbidity and mortality.  The magnitude of the problem does not attract anybody’s attention as TB disables and kills very slowly unlike Ebola or tsunami which grab national headlines.

Incorporating domiciliary treatment, the ‘National Tuberculosis Control Programme (NTCP)’ was established in 1962.  As it didn’t yield the expected results, the programme was modified as ‘Revised National Tuberculosis Control Programme (RNTCP)’ during 1993 to 1998.  Since 1997, 'thrice-weekly' regimen was being followed by the RNTCP.  As this regimen was thought to be associated with increased incidence of drug resistance and relapse, WHO recommended 'daily drug' regimen in 2010 to be adopted by the RNTCP.  And it took seven long years for our authorities to launch the change to the 'daily regimen' in November 2017 !  (http://pib.nic.in/newsite/PrintRelease.aspx?relid=173607).   Imagine the contribution to drug resistance and relapse by the TB control programme.   And, how "Directly Observed" is the "Directly Observed Treatment, Short-course (DOTS)" ?  And, the problems encountered in "Directly Observed" and the ground realities are well detailed in  http://www.thehindu.com/sci-tech/health/Improving-access-to-DOTS-is-crucial/article14580472.ece ... the detail gives the reason why it could not be "Directly Observed" here while it could be in Singapore ... of course, they have draconian methods to ensure regular intake of DOTS drugs strictly as per the protocol.


      The authorities which kept on painting a rosy picture had a zillion-volt shock when a report released on the eve of World TB Day (2012) by the World Health Organization (WHO) stated that ‘India presents a dismal picture having the highest number of MDR-TB cases in South East Asia’.  As a knee-jerk reaction, another “revision” of the RNTCP took place with the draft versions of the Joint Monitoring Mission(JMM) and the National Strategic Plan for tuberculosis Control (NSPTC) 2012 -2017 setting the road map for RNTCP for the next five years.  Thus, we are completely disillusioned with the TB control programme.  I don't place the blame entirely on doctors or other staff members of the 'Programme', as there are several factors beyond their control.  Many of them do what they are programmed to do according to the protocol and project a praiseworthy picture which they are expected to do (to please the bosses).  And, like all "good" officials, those concerned with TB have the challenge to try and minimise the implications of damaging data.  And the statistical data on health and disease in India don't enjoy a lot of authenticity and credibility. The whole world was mislead to believe that TB was controlled in India.  This is a prime example of the welfare schemes being far removed from the picture that organisers paint on paper.   Work culture, from top to the bottom, is a factor of paramount importance in translating theoretical projections into practical achievements.  People who visited workplaces in very successful countries know the difference.  The past and the present strategies to contain the dreaded scourge are theoretically excellent, but, but … (the pessimism is intended).

PUBLIC   PRIVATE   PARTNERSHIP                                                                                                           

Then is invented the catch-term “Public Private Partnership”.  Apart from four other objectives and improvements, the main thrust in the new strategy is to extend RNTCP services to patients diagnosed in the private sector as it is estimated that 60 to 80 per cent of the TB cases in the country are treated by private doctors.  It is now projected that ‘Public Private Partnership (PPP)’ would be a game-changer for the TB programme.

 Hence, another mantra is being chanted: 'Go where the patients go' (private practitioners).  But there are enormous gaps across the patient care cascade in the private sector.  To close the gaps and streamline the system the idea of pan-India engagement, coordination and motivation is mooted.  Thus, a consortium of various bodies and schemes are involved to rope in the private sector -- National Strategic Plan (NSG) to eliminate TB by 2025;  William J. Clinton Foundation (WJCF);  Clinton Health Access Initiative (CHAI);  Centre for Health Research & Innovation (CHRI);  Foundation for Innovative New Diagnostics (FIND India);  The Global Fund to Fight AIDS, TB & Malaria (GFATM);  Joint Effort for Elimination of Tuberculosis (JEET) to bring all these under one umbrella; Central TB Division (CTD) of Ministry of Health & Family Welfare;  State TB Office (STO);  WHO,  etc.  Eh ? What's this, too many cooks ?    ... spreading the risk of bearing responsibility makes one comfortable ... (pun intended) ... let's see whether the joint venture would tame the terrible TB.  And, in addition,  the 'offers' are there --  monetary support of Rs.500 per month to the patients during treatment and monetary incentive of Rs.1000 per case to doctors for notifying and giving drugs at the government's cost.  But where are the takers ?
                                 
For obvious reasons, there can be neither  interest, commitment nor capacity in the private sector to meet with the protocols and expected responsibility.  Because of this, the projected success of the revised and re-revised strategies may just be a chimera.  A programme which has failed over half a century can’t be expected to do wonders with a little more revision.  Why all this hoo-ha ... singing the same chorus in a different style ?

RITUALISTIC  EXHORTATIONS

        The annual rituals of conducting rallies, delivering sermons and hosting seminars on the World TB Day (March 24) have been going on mechanically.  Statistics rolled out in India must be viewed keeping in mind that the infrastructure is plagued by lack of well-structured and genuine reporting systems.  In the midst of all the brouhaha, one would leave the platform with a sense of déjà vu.  All the theatrical activity dissipates quickly, much like the fizzling out of the effervescence from a soda bottle.  Hackneyed  gestures and lackadaisical efforts are common.   One who follows up these acts would see the great farcical dimensions.  Grand pronouncements and rhetoric do not meet reality.  


STATISTICAL  FICTION
             On paper, everything seems to be genuine – planning, execution, accounting, results, democratic procedures, elections, technical jobs, professional dealings, and you name it. It may sound a triffle ironic, but the power honchos and the highly talented decision making bureaucratic brains are not necessarily the best or smartest people around.  Even the best planners in our set up run around in circles which is the easiest and conventional way.  We seem to have become experts in writing ‘statistical fiction’.  The much-touted achievements are part of this fiction.  Infrastructure is plagued by utter lack of well-structured and genuine reporting systems. Officials cook the books to please their bosses or to retain their seat.  None takes the statistics on health and disease in India without a pinch of salt.  If the statistical data are false,  it is natural that the results of the programmes based on them would be disappointing.
                                      “Lies, damned lies and statistics.”
                             --   Benzamin Disrael


‘TB’ for ‘Tuberculosis;  ‘TB’ for ‘Time Bomb’ ! 


WORLD  TB  DAY    March 24




What joy is it to celebrate the ‘World TB Day’ today when 1,000 persons are dying due to tuberculosis (TB) today in India as on any other day during the recent years ?  And, what pleasure is it to celebrate when doctors are threatened to be put in jail for not giving some information about their TB patients to the district officials ?  A notification made public on March 16, 2018 by the Union Health Ministry spelled out that doctors, chemists, hospital staff and druggists can be punished with jail term of six months to two years for not informing government authorities about their tuberculosis (TB) cases.   In India, TB was made a notifiable disease – like some diseases required by law to be reported to government authorities – in 2012, but not many cases were notified.  And, there was no provision until now to take penal action if cases were not reported.

            This is another joke in the infamous history of TB in India;  another knee-jerk reaction generated out of frustration, desperation and depression borne out of an empty feeling of not knowing what to do with the exploding drug resistance and the 'more than 1,000 deaths per day due to TB in India today'.  It’s like bolting the stable door after the horse has bolted !  

            In 2017, they thought that “Public Private Partnership” was the game-changer in the control of TB. And, in 2018, it is putting the doctors behind the bars and bringing the ‘National Strategic Plan’ to the fore, and  to 'Go where the patients go' !   Every year, on the occasion of ‘WORLD  TB  DAY’ they get novel ideas.  On paper, through legislation, we had already put an end to food adulteration, dowry evil, rape devils, crony capitalism, roaring corruption, booming bribery, and what not !  Did we not !  We don't take bribes, only "gifts" and "incentives" ...  we have to wait and see if the 'incentives' of Rs. 500 & Rs. 1000 would work in controlling TB. 

 And now we can relax as we seem to have solved the TB problem also by ensuring notification of the TB cases through legislation !!! With this draconian legislation, it is expected that most of the TB cases treated in the private sector (2 million -- more than half of the total number of the cases, according to the  study by Imperial College, London) would come into the official information net and thus followed up to the scientific completion of the treatment.  Reel is very different from real in our country.  The legislation may be ignored, or, if at all it is strictly implemented, the private sector doctors may just not treat the TB patients just as they don’t touch road accident victims or medico-legal cases, mostly.  By doing so, they don’t lose anything significantly.  Even otherwise, generally, the trend is to shun from treating TB patients for various reasons. Then who is going to handle this huge chunk of cases not cared for by the private sector ?  Government ?  There is no dearth of laws.  Only their implementation leaves much to be desired.   Responsibility is scattered and the punishment for violation of norms is too mild to be a deterrent.

            
Then, what is the effective solution?    

EFFECTIVE   SOLUTION

          Tuberculosis control is a quirky conundrum,  plagued by an abundance of problems and no clear solutions.   If the medical mess is about uncontrolled regimens of treatment,  burgeoning drug resistance and flagrant violation or ignorance of treatment guidelines,  it is also about bad infrastructure -- designed and executed poorly with absolutely no realistic foresight.   That is exactly why any revision after revision of the control programme is making health officials lose sleep.  
                 First,  let us have an idea about the problem.  The problem has been persistent, and increasing due to  (a) lack of a really effective vaccine to protect the population (TB would have become a thing of the past just as smallpox or polio if a very effective vaccine could be made – the BCG vaccine that is available does not totally protect against TB),  (b)  long duration of treatment (minimum 6 months) which most do not complete and end up as dangerous reservoirs of infection,  (c)inadequate and irregular treatment which results in drug resistance and keeps the reservoir of infection alive,  (d) spread of the disease by air through bacilli, coughed out by patients, which may remain infective for long periods – even months – and which may be carried by air to far away places to infect people everywhere,  (e)  low socio-economic living conditions which cannot be improved in the near future, and (f)  enormous segment of undiagnosed cases which spread the disease silently.  (g)  Irrational prescriptions by qualified doctors and by quacks which are common place in India.  (h)   irregular intake of drugs which is very common ... needless anti-TB treatment is also hazardous  
(i) huge presence of HIV and diabetes which favour development of TB   (j)   immense social stigma attached to TB and HIV which makes the people not to come out openly for treatment ... they silently spread the disease until they are stopped by death. 

If we take all these factors into consideration, it would be obvious that the most important plan to prevent and control TB is to detect all the cases of TB and treat them properly to make them all non-infective, if necessary, in a dictatorial way as is being done in Singapore or China.  To carry out this plan, the people at the helm of affairs should think outside the box of RNTCP and radically pursue a different course rather than just trying to prop up unsuccessfully again and again through revisions of the programme.  Antiquated disease control policies are legacy walls built by economic rules and regulations ... it requires a cerebral effort to bring down the walls of the traditional thinkers.

It is a gargantuan problem, but not an insurmountable one. The solution lies in the radical initiative of taking over the entire responsibility of detecting and treating TB throughout the country (which should include nutritional and economic assistance to the family members of the patient during the long period of treatment) responsibly, properly and exclusively by the government, as a vertical programme governed by an administratively and financially autonomous body, if necessary by creating a separate Ministry.  It is important to be autonomous,  as we all know too well how the game of governance – a game of handball between Ministries, Departments and Organisations – is played in our set up.   
                                                                                                        
It means that anyone outside the government facilities should not treat TB patients.  Once the diagnosis is made by a private practitioner, the patient has to be referred to the government agency for treatment.  The agency would be endowed with all the means, powers and teeth to ensure perfect treatment, and isolation, if necessary, to make sure that the patient would not transmit the disease to others.  It also means that TB drugs shall not be available in private medical shops (as in Brazil and Singapore).  This may seem to be utopian and quixotic but this is the only sure way to contain the insurmountable and invincible scourge.  Then the ready-made question springs up: "Where is the money for all this?"


Where are we getting the enormous money for space research and such things from?  That is from the government’s riches.  On March 31, 2018, India lost Rs. 270 crore due to the failure of a single satellite (GSAT-6A). About private riches, Indians have an estimated $462 billion, or about Rs.26 lakh crore, in tax havens abroad, according to Global Financial Integrity, a Washington-based think tank (October, 2014).


                Should we be proud of sending space vehicles to Moon and Mars or should we hang our heads down when 1,000 persons are dying every day due to TB in India as it is today?
    “O  miserable abundance,  beggarly riches."                                                                                 --John Donne

 (Dr. T. Rama Prasad is a former Medical Superintendent of the Ramalingam Tuberculosis Sanatorium  &  Perundurai Medical College and Research Centre, Perundurai.  His email ID is drtramaprasad@gmail.com)
                                                                                                                                                                                                                                                                                                                                                                                       


 
  
References:  

The following published articles were written by Dr. T. Rama Prasad.  (For more articles by this author, go to the title "About me and my Scribblings" on this blog / website.)

 1.      Drug Resistance in Tuberculosis  -  Journal of the Indian Medical 
        Association,  Vol.  64, pp. 264-267,  1975.
 2.    Childhood Tuberculosis - Part I - The Antiseptic, Vol. 76, pp. 449-504,1979
 3.    Childhood Tuberculosis - Part II - The Antiseptic, Vol. 76.  pp. 567-574, 1979
 4.    Short-course Chemotherapy - The recent Advances in the Treatment
        of Respiratory Tuberculosis - Current Medical Practice, Vol.24,
        pp. 41-46, 1980.
 5.    Drugs in the treatment of Tuberculosis - The Antiseptic
        Vol. 75,  p.678, 1978
 6.    Chemotherapy of Tuberculosis - The Antiseptic,  Vol. 76,  p.248,  1979.
 7.    Streptomycin in Tuberculosis - The Antiseptic,  Vol. 76,  p.516,  1979.
 8.    How effective is the TB control programme ?  (Special Article) -  
        The Hindu,  Vol.100,  No. 274,  p.8,  1977.
 9.    Five years Plans and TB Control Programme (Special Article) - 
        The Hindu,  Vol.101, No. 275, 
10.   National Tuberculosis Control Programme -  views presented,  
        on invitation  by theTuberculosis Association of India,  at the 32nd 
        National Conference on  Tuberculosis and Chest Diseases,  1977.
12.   Correlation between Geomagnetic Activity and Haemoptysis -
        paper  presented at the II Tamil Nadu State Conference on Tuberculosis 
        &  Chest Diseases,  1980.

       THIS  IS  AN  ABRIDGED  TEXT  OF  MY    'SCRIBBLING'.     FULL  TEXT  WILL  BE  POSTED  LATER.        --  T. Rama Prasad


Dr. T. Rama Prasad

'PAY WHAT YOU CAN’ Clinic, Perundurai, Erode Dt., TN, India., 

Former Medical Superintendent (Special), RTS & IRT Perundurai Medical College and Research Centre, Perundurai.

Website: www.rama-scribbles.com & Blog: https://drtramaprasad.blogspot.com & Twitter: @DrRamaprasadt & Facebook: T Rama Prasad & E-mail: drtramaprasad@gmail.com & WhatsApp: +91 98427 20393.








TUBERCULOSIS in 2026

  

 

 

 







 

 

             kkk   TUBERCULOSIS   in   2026

The following is the meta-analysis in brief by Global Data Study with particular reference to an article by Dr. T. Rama Prasad and VeSsha Rajeev.

" ... In early 2026, tuberculosis (TB) remains a very serious public health problem in India. The country’s ambitious goal to eliminate TB by the end of 2025 — set under the National Tuberculosis Elimination Programme (NTEP) — has not been achieved. Elimination, in this context, refers to a drastic reduction: an 80% drop in new cases and 90% in deaths compared to 2015 baselines (per India’s NTEP definition), or reaching very low levels like <1 infectious case per million population (per stricter WHO-aligned definitions).

The attached document (an article by Dr. T. Rama Prasad and Versha Rajeev, published in The Antiseptic) provides a realistic, critical assessment written at the close of 2025. It highlights significant progress in diagnostics, treatment coverage, and notification, but emphasizes persistent high burden, drug resistance, socioeconomic factors, and gaps in ground-level implementation. The authors conclude that the 2025 target is unattainable, and elimination may take many more years, potentially requiring major socioeconomic uplift or a breakthrough vaccine.

Key Data from WHO Global Tuberculosis Report 2025 (Released in November 2025)

According to the most authoritative recent source (WHO data covering up to 2024, with estimates and trends relevant into 2025–2026):

  • India’s estimated TB incidence rate fell by 21% from 237 per 100,000 population in 2015 to 187 per 100,000 in 2024. → This is nearly double the global average decline (~12%), and India showed one of the strongest improvements worldwide.
  • India still accounts for ~25% of the global TB burden — the highest of any country — with roughly 2.6–2.7 million estimated new cases annually in recent years.
  • Deaths declined from ~28 per 100,000 in 2015 to ~21 per 100,000 in 2024.
  • Treatment coverage improved dramatically: from ~53% in 2015 to over 92% in 2024, with very high success rates (~90%) for drug-susceptible TB.
  • “Missing” cases (undiagnosed/unreported) dropped sharply from ~15 lakh in 2015 to under 1 lakh in 2024.
  • Drug-resistant TB remains a major concern — India accounts for a large share (~32%) of global multidrug-resistant/rifampicin-resistant (MDR/RR-TB) cases.

Despite these gains, the progress falls far short of the 2025 milestones (50% incidence reduction and 75% mortality reduction from 2015 per WHO’s End TB Strategy). India did not achieve the stricter national goal of “elimination” by 2025.

Notified Cases in Recent Years (from Ni-kshay Portal & Reports)

  • 2020: ~18 lakh
  • 2021: ~21 lakh
  • 2022: ~24 lakh
  • 2023: ~25–26 lakh
  • 2024: ~26 lakh+ (with high notifications in early 2025, e.g., ~6 lakh in first 3 months of 2025 campaigns)

The rise in notified cases reflects better detection (not necessarily more disease), but the estimated incidence remains stubbornly high.

Current Status in 2026

  • TB is not eliminated — India continues to bear the world’s largest burden.
  • Two deaths occur every three minutes from TB in India (per various estimates).
  • Latent infection affects a large portion (~40%) of the population, with risk of progression to active disease.
  • Challenges persist: drug resistance, diagnostic gaps (especially in rural areas), socioeconomic factors (poverty, malnutrition, stigma), occasional drug shortages, and uneven implementation across states/districts.
  • Positive developments include expanded molecular testing, shorter regimens (e.g., BPaLM for MDR-TB), nutritional support (Ni-kshay Poshan Yojana), and community involvement (Ni-kshay Mitras).

The attached article’s pessimistic yet pragmatic tone aligns well with WHO and other data: impressive efforts and improvements, but the tenacious nature of TB (large latent pool, airborne spread, resistance, and social determinants) means true elimination remains years away — likely requiring sustained multi-sectoral action, better funding, and possibly new tools like an effective adult vaccine.

In short: Progress is real and commendable, but TB is still very serious in India in 2026, and the 2025 goal was not met. The journey continues into the coming years. ... "

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     A MONTHLY JOURNAL OF MEDICINE AND SURGERYS

           ISSN  0003 5998

 Indexed in  IndMED       Email: admin@theantiseptic.in    www.theantiseptic.in

ELIMINATION  of  TUBERCULOSIS  by  2025


RAMA  PRASAD  T.    and     VERSHA  RAJEEV                                                                         

Dr. T. Rama Prasad,

Formerly:   Medical Superintendent (Special)  of  Ramalingam Tuberculosis Sanatorium & IRT  Perundurai Medical College and Research Centre,  Perundurai, Tamil Nadu.           

Presently:  Director & Senior Consultant in TB and Lung Diseases  of  ‘PAY WHAT YOU CAN’ Clinic, Perundurai,   Erode District, TN – 638052.   

Ms. Versha Rajeev  (Co-author)

MBBS  student,  Sri Ramachandra Medical College,  Chennai.


Specially Contributed to  “The Antiseptic”  

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“Science like life, feeds on its own decay.  New facts burst old rules;  then newly divined conceptions bind old and new together into a reconciling law.”   

                                                                                                   --  William James

ABSTRACT

True to this quote, a ‘Revised National Tuberculosis Control Programme (RNTCP)’ emerged out of the decay of the ‘National Tuberculosis Control Programme (NTCP) of 1962.  And the revised programme of 1993 gave birth to the ‘National Tuberculosis Elimination Programme (NTEP)’ in 2020.    Though the approach, innovation, and implementation are slightly different, the old and new components are bound together with the common objective of eliminating or eradicating tuberculosis (TB).  The effects of the dynamic strategy to ‘eliminate’ the insurmountable scourge by 2025, the formidable defenses of the resistant bacillus, the gains and disappointments during the NTEP war, and the possible ways to win in the next battle are briefly outlined in this semiformal writing.  In this scenario of the seemingly unending battle fought by multiple means, let’s hope for that stroke of serendipity which may facilitate elimination of this monstrous killer, in the near future, if not by the end of 2025.

Key words:  Tuberculosis (TB), Elimination,  National Tuberculosis Elimination Programme (NTEP),  WHO’s Global Tuberculosis Report 2025,  Coinfection of COVID and tuberculosis,  

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Introduction 

2025 is set as a goal to ‘ELIMINATE’ tuberculosis (TB) from India by the Government of India.  Now that we have reached the end of 2025, it is time to take stock and have a look at the scenario.  On November 13, 2025, media ran the headline “Tuberculosis incidence falling in India by 21% a year : WHO report”  on the occasion of the release of the ‘Global TB Report 2025’ of the World Health Organization (WHO).  The report paints a positive picture about the anti-TB activity in India in the recent years while cautioning about the immense burden of the disease still in the country and the world at large. Some of the relevant facts and figures related to the elimination of the disease are briefly mentioned in this article in a semiformal format.

Vega's query on TB elimination in India

Vega,  a medical student, posed a poignant question: “With over 40% of India's population harbouring ‘latent’ tuberculosis germs -- infected but not diseased -- can we eliminate TB by the end of 2025 (the goal set for itself by the government), or even in the coming years, with the kind of TB burden that the country has ?”   About 10% of these ‘latent’  cases may progress to active lung TB due to waning of immunity from ageing, diabetes, or other factors. These patients can then transmit the disease to the healthy population in future.  And, of course, the country is loaded with TB bacilli and pollution.  There is no fully effective vaccine.  How to prevent ?  But, there is a close relationship between economic development and TB.  So, elevate the socio-economic status.  This is the answer.    As John F. Kennedy famously said, “a rising tide lifts all the boats !”  And the defiant TB would go down !  Socioeconomic development is the best vaccine.  It would eliminate all evils.  But when ?   HALLELUJAH  !   2026  SANS  TB  !   NO  ?

Dear Vega, eliminating TB by 2025 is not the crucial issue.  It may take some more years.  The government set an ambitious goal for itself and worked hard for it.  The missionary zeal is to be appreciated.  Most of us couldn’t complete the construction of our houses as per our time plans.  That’s the norm, not a failure.  No regrets.  Better late than never.  Now, let us go to our numbers (statistics) for whatever validity they stand for !

What’s  elimination ?

Elimination means a drop of 80% in new cases and 90% in deaths from 2015 baselines, according to the National Tuberculosis Elimination Programme (NTEP) of India 1. The World Health Organization (WHO) recognises ‘elimination’ as achieving an incidence of less than one case of infectious TB per million population or a prevalence of latent TB infection of less than 1% . Several countries have already reached the TB elimination phase; others are expected to do so in the foreseeable future. The TB elimination phase is defined as an incidence of fewer than 20 cases per 100 000 population.

Going by this definition, less than around 1,455 cases would mean that TB is eliminated in India.  But the Centre’sNi-kshay portal has already recorded 5,97,987 new TB cases in 2025 in India.  The numbers, by any definition, may be slightly less than that of the previous years, but it's not flattering enough to call it anywhere near the "ELIMINATION" point.  That is expected, and the authorities need not hate to acknowledge, but plan to upgrade the system.

TB Elimination is not eradication (0%).  Eradication is the reduction to zero of the incidence of a particular disease in a defined geographical area as a result of deliberate efforts.   TB, characterized by the large reservoir of TB infection,19 cannot in fact be eradicated just as some other diseases like poliomyelitis.  Elimination means to reduce to a very low level the incidence of TB and keep it low, so as to prevent any further rise.

Global scenario  

The Global TB Report 2025 states that TB remains one of the world’s deadliest infections, claiming over 12 lakh lives and affecting an estimated 1.07 crore people in 2024.  India bears roughly a quarter of the global TB burden --  India (25%), Indonesia (10%), the Philippines (6.8%), China (6.5%), Pakistan (6.3%), Nigeria (4.8%, Congo (3.9%), and Bangladesh (3.6%).  These may just be the numbers provided by the authorities.

The report said that despite measurable progress in diagnosis, treatment and innovation, persistent challenges in funding and equitable access to care threaten to reverse the hard-won gains in the global fight against TB. The report mentioned that timely treatment for TB saved an estimated 8.3 crore lives since 2000, globally.  It is a creditable achievement.

Recapitulation  

Tuberculosis (historically known as Phthisis, Consumption, White plague, White death, Captain of death  and The captain of the men of deathhas been with the humanity for a very long time – it can be traced to the prehistoric ages (the remains of Pleistocene bison in Wyoming gives evidence of presence of TB over 17,000 years ago).  And the cause for the disease was identified around one-and-a-half centuries ago (Robert Koch announced the discovery of the causative bacillus, Mycobacterium tuberculosis, on March 24, 1882).  

Over the past half-a-century, we could not satisfactorily control TB though we had specific drugs to treat.  In stark contrast, COVID jolted and upended the entire world for a few years and quietly receded.   In the same kind of contrast, I (T. Rama Prasad) wrote 28 articles on COVID in this journal, The Antiseptic, in 30 months (a world record of sorts) and stopped writing on COVID as it faded from focus.  But, I had been writing for over half-a-century on TB which is still a subject of debate !!!  Some (16) of my writings related to TB are indexed in the ‘REFERENCES’ listed at the end of this article 3 to 18 .  The contrast is due to the peculiarity of the TB bacillus, more tenacious than the corona virus.

Half-a-century ago, my article titled “Drug Resistance in Tuberculosis” was published in the Journal of the Indian Medical Association (1975) 10 .  And, THE HINDU published as ‘Special Articles’ two of my writings on TB control titled “Five Year Plans and TB Control Programme (1978) , and “How Effective is the TB Control Programme ? “ (1977) .  And, my views were presented on the National TB Control Programme at the National Conference on Tuberculosis and Chest Diseases (1977) 17 .  All were around 50 years ago.  My suggestions presented half-a-century ago through these platforms were not taken seriously by the experts at the helm of the affairs at that time as they had the hubris that TB could be eliminated by the National TB Control Programme (NTCP) by the end of 1970s or 1980s.  Now, in 2020s, we are still struggling to eliminate the disease !

  One of us (Versha Rajeev) wrote in Health journal in November 2020 : “… around one lakh people died in India as on October 15, 2020 in nine months due to COVID-19. It is a small number compared to 4,35,000 deaths due to T B annually …” 24  , 25. The entire mortality due to COVID over the years in India (five lakhs) is only a little above the number of deaths due to TB per year.

The unending journey

The journey to contain TB in India started with the systematic establishment of the ‘National Tuberculosis Control Programme (NTCP)’ in 1962.  As it didn’t yield the expected results, the programme was modified as ‘Revised National Tuberculosis Control Programme (RNTCP)’ in 1993.  As this also fell short of the expectations, a crash programme called the ‘National Tuberculosis Elimination Programme (NTEP)’ was launched in 2020 with the ambitious target to eliminate TB from the country by 2025.  Now, we are at the end of 2025, staring at the performance. The programs have been theoretically very sound, based on robust scientific studies and conceived by international health bodies.  Some concepts failed in the field conditions due to hurdles in the ground realities, though.  Hopefully, the peregrinations would find the light at the end of the tunnel soon.

The status of ‘Elimination by 2025’  

This deadline of 2025 is pivotal for India's ‘National TB Elimination Programme (NTEP)’, which ambitiously targets TB elimination five years ahead of the WHO's 2030 goal prescribed by the ‘UN Sustainable Development Goals’ (SDG).  Elimination means an 80% drop in new cases and 90% in deaths from the 2015 baselines.  If one goes through the 'India TB Report 2018 : Annual Status Report',  one gains the impression that there is a committed  political will and a strong programming strategy in place to reach the goal of ending TB in India by 2025,  in line with the 'National Health Policy, 2017'19 .

The Central Government has aggressively worked towards elimination of TB by 2025.  The ‘National Strategic Plan (2017-2025)’ drives this through initiatives like the ‘Pradhan Mantri TB Mukt Bharat Abhiyaan (PMTBMBA).  It mobilized over 2.59 lakh community volunteers --‘Ni-kshay Mitras’ -- to offer nutritional and financial aid to 1.18 crore patients.  Under the ‘Ni-kshay Poshan Yojana (NPY)’Rs 3,202 crore has been disbursed through the Direct Benefit Transfer (DBT) --  Rs 1,000 per month per patient for the entire duration of treatment.  The largest TB laboratory network in the world, comprising 9,391 rapid molecular testing facilities and 107 culture & drug susceptibility testing laboratoriesare in place.  

‘100-day TB Elimination Campaign’ in December 2024 ramped up diagnostics with over 500 AI-powered portable X-ray machines (in addition to the 1,500 machines with the States / UTs), screening over 5 million people, and drones for supplying remote areas.   And, services were decentralised through 1.78 lakh Ayushman Arogya Mandirs across the country, and ASHA workers have been trained to do the job.  These efforts slashed "missing cases" by 83% since 2015 and hit 87.6% treatment success for drug-susceptible TB in 2022 cohorts.  

According to the ‘Global TB Report 2025’ of the WHO, released in November 2025, India recorded, between 2015 and 2024, a 21% fall of incidence (new cases emerging each year) of TB from 237 to 187 per lakh of population, almost double the rate of decline observed globally;  a fall of death rate from 28 to 21 per lakh of population;  a reduction of the “missing” cases from 15 lakh to one lakh;  an increase in treatment coverage from 53% to 92%;  and a credit of diagnosing 26 lakh out of the estimated cases of  27 lakh; a treatment success rate of 90%, against the global average of 88%.  Such a progress is highly commendable.  

Thus, India has made significant strides in reducing TB cases and deaths, but achieving elimination by 2025 or even in the next few years remains a formidable challenge. While treatment coverage has expanded and case numbers have declined, the country still bears more than a quarter of the global TB burden.

The other side of the coin  

Optimists danced around.  Pessimists called it a statistical aberration, saying that according to the 'Global Report of 2017',  the estimated incidence of TB in India ( 2.8 million)  accounts for a quarter of the world's TB cases and that India continues to lead the world in tuberculosis cases, accounting for around the same number in 2024 (2.6 million), according to the WHO's Global Tuberculosis Report 2025. Not a great reduction. Though India has reduced TB rates since 2015, it remains far from its elimination goal set for 2025, they say.  True,  according to the information, 18,05,670 cases of TB were reported in 2020, 21,35,830 in 2021, 24,22,121 in 2022, 25,52,257 in 2023, and 26,17,923 in 2024, indicating a persistent rise, with the rate of cases per lakh of population being 131 in 2020, 153 in 2021, 172 in 2022, 179 in 2023, 183 in 2024, and 195 in 2025.  India sees a 1.5 fold rise in the cases amidst expectations to eliminate TB by 2025, according to the RTI reply published in The Week of 2025/11/20 20 .

( Despite 2025 goal to eliminate TB India sees 1.5-fold rise in cases RTI reply - The Week

www.theweek.in › national › 2025/11/20 › des76-dl-tb-cases-rise )

Not palatable  

According to the "Global TB Report 2024" and the "India TB Report 2024",  more than one-fourth (30 lakh people) of the world's new TB cases are in India,  and more than three lakh people died due to TB, in 2023.  Incidence of TB had increased slightly to 27.8 lakhs in 2023 from 27.4 lakhs in 2022.  Deaths due to TB remained the same in 2022 and 2023 at 3.2 lakhs.    The incidence of TB in India is around 195 per one lakh of population,  and the deaths due to TB are around 22 per lakh of population  --  alarming figures.  According to one source, “India has notified 19.88 lakh TB patients (Jan - Sept 2024) as compared to 19.08 lakhs during the same period in 2023, a 4.2 per cent delta increase.”  And,  the Union Health Ministry’s 100-day TB detection campaign, which started on December 7, 2024 and ended in March 2025, found over six lakh new TB cases in India. This shows that if we look for the cases, they are there in abundance.  All this is not palatable to India which declared the goal to 'eliminate' TB from the country by 2025.

A September 2025 analysis reveals stagnant patient numbers in high-burden spots like Mumbai's Govandi slums,where TB strikes nearly every second household. The historical programs, the ‘National Tuberculosis Control Programme (NTCP) and its revision ‘Revised NTCP (RNTCP)’ had repeatedly fallen short of the projections in high-burden zones.  Now, the NTEP (since 2020) is under scrutiny.

A puzzling paradox

TB is a puzzling paradox.  The infecting germ was identified about 150 years ago and effective drugs were discovered decades ago while it is still a struggle to control / eliminate the disease.  Unduly positive official propaganda made people complacent while 'drug-resistance' has become a menace.  Numerous initiatives have been in place to contain the seemingly invincible and insurmountable scourge while the most important asset of having 'DEDICATED WORKERS' is not much noticeable.  While aspiring for a five-trillion-dollar economy, India is puzzlingly handicapped in its endeavour to stop a well-understood disease which is preventable and curable, even as it inaugurated the ‘WORLD’s  LARGEST aeroplane engine MRO on November 27, 2025 at Hyderabad.

Unattainable goal

While the projected progress is highly praiseworthy,  the goal could not be achieved for various reasons.  In spite of the rosy picture, seen through the official lens of statistics -- potentially glossing over the bitter grassroots realities -- the 2025 target is certainly out of reach.  It may not be within the reach even in the next few years.  Why ?  Diagnostic gaps persist: Sputum microscopy covers just 75% of tests, molecular diagnostics only 25%, enabling silent transmission. The COVID-19 pandemic derailed screenings and drug supplies.  Socioeconomic hurdles -- stigma, out-of-pocket expenses despite free drugs, and staff shortages in under-resourced clinics -- undermine treatment adherence.  And, the “business-as-usual” attitude persists.

 A high burden of drug-resistant TB, weak healthcare infrastructure, especially in rural areas, socio-economic disparities,  drug supply chain disruptions,  shortage of dedicated and trained personnel,  shortage of drugs, etc. remain as the key issues to be addressed.    Dedication to work at the grassroots level is of humongous importance both for immediate and long-term results; and it is too much to expect in a huge heterogeneous country, especially in a government programme of inherent inertia.  There is a gross variation of dedication, motivation and honesty across districts and States in the vast country. All these are to be addressed for the elimination drive to be successful.

TB vaccine

Making an effective TB vaccine could have put an end to the disease long ago.  There has been no fully effective vaccine against TB in adults (BCG vaccine protects only to some extent against development of some forms of TB in children).  It is unfortunate that an effective vaccine against TB couldn’t be developed though the disease has been with the humanity for a very long time.  In stark contrast, the expected time of 10 years to produce a vaccine for a coronavirus is ‘compressed’into 10 months, and the COVID seems to have made a quiet exit.   

Down memory lane

Half-a-century ago, in The Hindu on April 28, 1977, I (T. Rama Prasad) foresaw and wrote this: "Development of drug resistance, from inadequate and irregular treatment, has far-reaching implications. If unchecked, it would render TB unmanageable by current methods, whatever the means. Irregular treatment keeps patients alive, suffering, and infective, disseminating drug-resistant organisms."  The WHO's ‘2019 Global Tuberculosis Report’ validated this, after about half-a-century, confirming that India leads in TB and Drug-resistant-TB cases.  TB now kills more than ever -- 1,000 daily in India, 3,500 globally -- with 30,000 new infections worldwide each day. When I entered the TB field half-a-century ago,  I imagined scarcity of TB cases for teaching purpose by the 2020s.  But it didn’t happen.

The menace of ‘Drug Rsistance’ 

Gaining resistance to the drugs by the bacillus is another reason for its persistence 10.  ‘Drug-resistant TB (DR-TB)’ exacerbates the crisis. In 2023, India reported 63,939 ‘Multidrug-resistant / rifampicin-resistant (MDR/RR)’ cases -- 2.5% of new patients and 16% of retreatment cases.  Prevalence surveys estimate MDR-TB at 5.4%, isoniazid mono-resistance at 11.4%, and rifampicin mono-resistance at 2.5%.  India accounts for much of the world's 1.4 million annual isoniazid-resistant cases.

The NTEP counters this with the credit of universal drug susceptibility testing (58% coverage in 2023) and shorter ‘all-oral’ regimens like the six-month ‘BPaLM’ (Bedaquiline, Pretomanid, Linezolid and Moxifloxacin), achieving 80% success for MDR-TB.  Treatment success for shorter MDR/RR regimens rose to 75% in 2022 (from 68% in 2020), and 73% for longer MDR/XDR cases, with 92% of notified DR cases starting second-line therapy.  The Global TB Report 2025 stated that there is no significant increase in the number of multidrug resistant (MDR) TB patients in India.  

False sense of achievement

The official data suggests effective containment, but the limited studies may understate the magnitude and excessively excite us to celebrate.  Public rhetoric around "elimination" breeds complacency, delaying diagnoses with dire outcomes. Without vigilance, the disease flares unchecked.  Let us not forget the laidback India during the ‘second COVID wave’ when India went on to indulge in ‘meetings and melas’ only to witness a spike of 4,00,000 cases a day in April 2021.  If people relax that way now, a new MDR TB wave would -- God forbid -- kill poorer countries where most of the TB is present.

TB and COVID-19: A tangled threat

Studies show that those with old healed TB lesions face worse lung impairment and quality of life if infected with COVID-19.  TB mortality risk is 1-3 times higher in COVID patients; the two diseases may mutually amplify each other; potential biological effects of the interaction between the two diseases may be existent -- a ‘Cursed Duet’..  The ongoing global study by the ‘Global Tuberculosis Network (GTN)’, backed by the WHO, will clarify this.  Ironically, curable and preventable TB endured a century-long battle, while enigmatic COVID-19 faded after a few years.  COVID disrupted TB plans, as it did for everything else, potentially derailing elimination timelines. Read my (T. Rama Prasad) articles titled “COVID and TUBERCULOSIS” 8,9. 

 

Though COVID does not seem to be of a serious concern now in 2025, its possible after effects on various systems of the people (who have been convincingly relating many of their present varied symptoms and diseases to the past COVID infection or vaccinationand on TB elimination are to be studied.  There is no sure way of proving the relationship.  They may be coincidental.  However, we had already seen the association of some unusual morbidities with COVID.  For example, the world’s first case of an association of COVID with TB, Yellow Nail Syndrome, and diabetes was documented by me (T. Rama Prasad) in this journal, The Antiseptic, of March 2023 .

  

Ground reality

 

NTEP's innovations and results -- doubling decline rates and boosting notifications -- build real momentum. But true elimination in the near future requires ramped-up funding, equitable access, and multi-sectoral commitment.  Experts call for closing the 2.5 lakh annual "missing cases" gap to prevent rebounds and to make India a global beacon. Much as we dislike grumbling about the efficiency of the control measures, the horrendous facts leave us with no choice but to package our message in a bundle of barbed wire.  India should take pride in its unicorns but simultaneously raise the bar.  We missed the chance to puff up our chest with the pride of elimination of ‘the captain of the men of death’.  And thus, we continue our peregrination in the ‘white plague’ quagmire. 

 

Rhetoric and reality

 

            Fostering undue complacency among the public through utterances of rhetoric of imagined achievements did more harm than good.  The magnitude of the TB problem does not attract anybody’s attention as TB disables and kills slowly quite unlike COVID, Ebola, or a tsunami.  The WHO declared TB a “Global Health Emergency” in 1993. And in 2006, the “Stop TB Partnership Development” and the “Global Plan to End TB” aimed to save 14 million lives between their launch and 2015.  It was a costed plan and a roadmap for a concerted response to TB.  On September 26, 2018, the United Nations (UN) held its first-ever high-level meeting on TB.  Apart from the “UN Political Declaration on TB”there are examples of high-level rhetoric and leadership on multisector accountability which include “Presidential or Head of State” and “End TB”/ “Race to End TB” initiatives, and formalized mechanisms for the engagement and accountability of stakeholders in various countries including India 

 

A number of targets were set, but not achieved in the real world 4,5.   Political will is the need of the hour, not verbiage, promises and pronouncements.  Given the state of pusillanimous global leadership, the partnership of Covid and TB would, for a long time, haunt the poorer countries where TB had been rampant.  The past is frequently the prologue in geopolitics.  

 

The leaders need to clear the phantoms from their heads and grasp the reality. The President of one country (Jair Bolsonaro) even declared that Covid vaccines turn people into crocodiles and mired down his Brazil in the mud of Covid 25.  Go to the cited reference and see the CROCODILE !!!  The President of another country (POTUS) touted some drugs unscientifically to control COVID and thought aloud as to why antiseptics were not injected to tame the virus !!!

 

The rich and the celebrities 

 

               And, though poverty and TB have a mutually reinforcing relationship,  the wealthy and the celebrities are also affected by TB as the disease spreads through air.  Even an aristocrat can’t have private air though he may have a private jet aeroplane.  Dubbed as Ebola with wings,”  TB flies freely from place to place.  Kamala Nehru, Mohammed Ali Jinnah, Srinivasa Ramanujan, Lennec, Lady Roosevelt, John Keats, Shelly and a host of other celebrities succumbed to TB ! 

 

Economic losses

 

“The economic burden of TB encompasses direct costs related to healthcare services and indirect costs stemming from productivity losses and premature mortality. According to a report by the World Health Organisation (WHO), TB costs India an estimated $24 billion annually in terms of lost productivity and healthcare expenses. This staggering figure underscores the magnitude of TB’s economic impact on the nation. 27.

 

A dire warning of the heavy financial perils of continuing to neglect tuberculosis is apparent from some studies. The researchers of a study projected a ‘business-as-usual’ scenario of 120 countries of 31·8 million tuberculosis-related deaths between 2020 and 2050, resulting in economic losses of $17·5 trillion 21.   If a 90% reduction in tuberculosis mortality were to be reached by 2030 (as specified in the Sustainable Development Goals), 23·8 million deaths would be averted, with costs reduced by $13·1 trillion.

A loss of nearly $300 million due to lost wages and a $3 billion indirect cost per year to the Indian economy is attributed to TB due to staff absenteeism and lost productivity between 1990 and 2019 22 .  Another study indicated that, “over 2021 to 2040, the health and macroeconomic burdens of TB in India will include over 62.4m incident cases, 8.1m TB-related deaths and a cumulative gross domestic product (GDP) loss of US$146.4bn.” 23 .

 

Vulnerable country  

 

India has the highest burden of tuberculosis (TB) with two deaths occurring every three minutes from TB.  TB seems to be invincible notwithstanding the admirable initiatives taken by the "National TB Elimination Programme (NTEP)" and the "National Strategic  Plan (NSP) for Tuberculosis Elimination (2017 - 2025) -- 'Mukt Panchayat Initiative', 'Jan Andolan', 'Pradhan Mantri TB Must Bharat Abhiyaan', 'Ni-kshay Poshan Yojana', etc.  Various steps have been taken in recent years to make India TB-free by 2025.   It's a tough job.  It's a tough bacillus.  Ergo, we are able to go to the Moon, but could not eliminate a microorganism !!!

 

According to the ‘Global TB Reports’ of the WHO, there has been a reduction of about 20% in the rates of incidence and death during the previous one decade, in India.   But, is this rate of progress enough to declare that we can bid TB adieu by the end of 2025 ?   Moreover, do these figures reflect the ground realities what with all alleged statistical manipulations to please bosses, especially before the computerization of the systems ?  The bosses had been fixated with the idea that the TB programme had been a grand success albeit the persistence of the pestilence.  They hate failures.

 

And on every ‘World TB Day’ (March 24),  a grand repeat of the same is enacted.   The annual rituals of conducting rallies, delivering sermons and hosting seminars on the ‘World TB Day’ have been going on mechanically.  Statistics rolled out in India must be viewed keeping in mind that the infrastructure is plagued by lack of well-structured and genuine reporting systems.  In the midst of all the brouhaha, one would leave the platform with a sense of déjà vu.  All the theatrical activity dissipates quickly, much like the fizzling out of the effervescence from a soda bottle. Hackneyed gestures and lackadaisical efforts are common.   One who follows up these acts would see the great farcical dimensions.  Grand pronouncements and rhetoric do not meet the reality. 

 

The way forward
          Tuberculosis control is a quirky conundrum,  plagued by an abundance of problems with no clear solutions.   If the medical mess is about uncontrolled and protocol-based regimens of treatment, burgeoning drug resistance, and flagrant violation or ignorance of treatment guidelines,  it is also about bad infrastructure -- designed and executed poorly with absolutely no realistic foresight.   That is exactly why any revision after revision of the control programme is making health officials lose sleep.  Reaching the goal of elimination of TB will demand sustained government commitment, stronger healthcare infrastructure, and focused interventions for vulnerable populations.

A more concrete solution lies in taking over the entire responsibility of detecting and treating TB throughout the country exclusively by the central government, as a vertical programme, governed by an administratively and financially autonomous body, if necessary by creating a separate Ministry (considering the  $24 billion loss per year due to TB in India  27 ).  It is important to be autonomous, as some are critical of the game of governance played in our set up – a game of handball between Ministries, Departments and Organisations.   It is to be autonomous headed by medical experts because it is alleged that many ‘babus’ “become cogs in the wheels of complacency and acquiescence, turn lazy and cynical, and worse, lose their moral compass”  --  go to the link below to know about our ‘babus’ 26 --  

-   https://timesofindia.indiatimes.com/blogs/toi-edit-page/has-ias-failed-the-nation-yes-and-its-not-all-politicians-fault-the-service-rewards-mediocrity-risk-aversion/  -- Has IAS failed the nation? Yes, and it’s not all politicians’ fault. The service rewards mediocrity & risk aversion”  is the interesting title of the article. )

 

 Even as this critique is being written, a report appeared today (The New Indian Express, November 25, 2025) of a strongly worded warning to ‘babus’ from the ‘Prime Minister’s Office 

urging them to shed “routine bureaucratic mindset” and focus on “value addition” keeping in mind the overall public and national interest.  TB control is more of a humanitarian problem 

rather than an administrative programme.




            Dear ‘Babus’, the ground realities of the silent killer must be brought out of the closet.  We have already lost precious years by fostering complacency and painting rosy pictures about our achievements, and by treating the victims like medieval leprosy patients, and worse, by pretending that TB is eliminated on our soil.  The real figures would scream out the impending nightmare !!!

 

Achtung !   TB is ‘to be or not to be’

An effective vaccine, like that of smallpox, could have ended this war long ago, and could have put a stop to writings like this, decades ago. A century of research yielded little; BCG offers only partial protection.  Can we greet 2026 as the first ‘TB-eliminated year’ for India?  Dream or doable ?  .

There is no ‘mantra’ to bid TB adieu.  It would take a long time, until we succeed in making an effective vaccine or making India a 5-trillion-dollar-economy.  Let us handle the right task at the right time.  Let’s remember the following quote of Chanakya, the iconic Indian intellectual who authored the ancient Indian treatise, Arthashastra:

 

“If the right task is not accomplished at the right time, then time itself wrecks the chances of success.” – Chanakya

 

REFERENCES

1. https://dghs.mohfw.gov.in/national-tuberculosis-elimination-programme.php

2. https://www.ncbi.nlm.nih.gov/books/NBK310760/

3. https://www.thehindu.com/opinion/open-page/a-bad-patch/article31069356.ece

4. Five years Plans and TB Control Programme (Special Article) -

   The Hindu,  Vol.101, No. 275,  November 24,1978

5. How effective is the TB control programme ?  (Special Article) -

    The Hindu,  Vol.100,  No. 274,  p.8,  1977.

6. https://drtramaprasad.blogspot.com/2017/04/yellow-nail syndrome_28.html

7. https://drtramaprasad.blogspot.com/2017/04/tuberculosis-in-india_29.html

8. Rama Prasad, T.,  COVID and Tuberculosis.  The Antiseptic, 2021  December;

    Vol.   118; No.12; P: 11-17;  Indexed in IndMED --  www.antiseptic.in

9. https://drtramaprasad.blogspot.com/2017/04/tb-and-covid.html

10. Drug Resistance in Tuberculosis  -  Journal of the Indian Medical

      Association,  Vol.  64, pp. 264-267,  1975.

11. Childhood Tuberculosis - Part I - The Antiseptic, Vol. 76, pp. 449-504,1979

12. Childhood Tuberculosis - Part II - The Antiseptic, Vol. 76.  pp. 567-574, 1979

13. Short-course Chemotherapy - The recent Advances in the Treatment

      of Respiratory Tuberculosis - Current Medical Practice, Vol.24, pp. 41-46, 1980.

14. Drugs in the treatment of Tuberculosis - The Antiseptic, Vol. 75,  p.678, 1978

15. Chemotherapy of Tuberculosis - The Antiseptic,  Vol. 76,  p.248,  1979.

16. Streptomycin in Tuberculosis - The Antiseptic,  Vol. 76,  p.516,  1979.

17. National Tuberculosis Control Programme -  views presented, on invitation  by theTuberculosis 

      Association of India,  at the 32ndNational Conference on  Tuberculosis and Chest Diseases,  1977.

18. Correlation between Geomagnetic Activity and Haemoptysis -

      paper  presented at the II Tamil Nadu State Conference on Tuberculosis&  Chest Diseases,  1980.

19.  https://tbcindia.gov.in/showfile.php?lid=3314

20. www.theweek.in › national › 2025/11/20 › des76-dl-tb-cases-rise

21.  Lancet Glob Health. 2021 doi: 10.1016/S2214-109X(21)00299-0. published online Sept 3. 

      [DOI] [PMC    free article] [PubMed] [Google Scholar]

22.  https://www.sciencedirect.com/science/article/abs/pii/S0019570722000452

23.  https://pmc.ncbi.nlm.nih.gov/articles/PMC11637336/

24.  Vol. 98 • NOVEMBER 2020   HEALTH 31     www.theantiseptic.

25.  https://drtramaprasad.blogspot.com/2023/01/versha-alias-vega.html

26.  https://timesofindia.indiatimes.com/blogs/toi-edit-page/has-ias-failed-the-nation-yes-and-its-not-all-   politicians-fault-the-service-rewards-mediocrity-risk-aversion/ 

27.  https://humana-india.org/blog/economic-impact-of-tuberculosis-in-india/

 

The  END  of  the  ARTICLE

 

BPaLM  Regimen

 

Vega, a medical student, showed me the front page news report in THE HINDU of September 7, 2024 with details of a new treatment regimen for ‘Multidrug-resistant Tuberculosis (MDR-TB)’  and asked whether tuberculosis (TB) can be eliminated from India by 2025 as envisaged, with the new treatment.  I said that we would be lucky if we don’t end up creating TB bacilli resistant to the new drugs (Bedaquiline, Pretomanid, Linezolid and Moxifloxacin of BPaLM regimen) also, let alone eliminating TB.  Outcome of TB treatment is not like mathematics.  Half-a-century ago, when ‘effective’ drugs were introduced, everyone thought that TB would be wiped out soon, and now with the introduction of a new regimen for MDR-TB, we seem to be assured of eliminating even MDR-TB soon.  

 

It’s the natural aversion to take medicines for a long time of six months or more that makes TB invincible and insurmountable,  not the dearth of effective drugs.

 




 


As Mark Twain famously said, “Facts are stubborn things, but statistics are pliable.”  The global hunger index, poverty index, and now TB data are all becoming proof that there are three kinds of lies --  lies, damned lies and statistics !!!

 

About the authors

 

Dr. T. Rama Prasad is the WORLD RECORD holder of authoring  28 articles related to COVID-19 in 30 months, published in a medical journal (The Antiseptic – www.theantiseptic.in -- Indexed in IndMED), and reporting in the same journal the WORLD’s FIRST CASE of ‘Yellow Nail Syndrome’ associated with COVID-19, PT & DM (https://drtramaprasad.blogspot.com/2017/04/yellow-nail syndrome_28.html ).    He wrote his first article in the premier journal, The Antiseptic, four decades ago.  Many of his articles written over half-a-century may be accessed at https://drtramaprasad.blogspot.com/2017/04/dr-t-rama-prasad.html   https://drtramaprasad.blogspot.com/2017/04/my-in-newspapers_28.html   &  https://drtramaprasad.blogspot.com  .    

 

He is the former MEDICAL SUPERINTENDENT (Special) of R.T. Sanatorium & Perundurai Medical College and Research Centre.   Presently, he is the Senior Consultant in TB & Lung Diseases, and the Director at  ‘PAY WHAT YOU CAN’ Clinic,  Perundurai,   He is the recipient of the “Lifetime Achievement Award” of the ‘Coimbatore Respiratory Society’, and the honorific title  “Perundurai Rathinam” from the body of  ‘Perundurai Public’.

A   BLOG  ARTICLE  in  :  http://drtramaprasad.blogspot.com  


../Documents/nnn/Portrait%2030.12.2019%202.jpg

A  brief  introduction

In the words of Prof C H Sivaraman, FRCP (London):

 “ ... Dr. T. Rama Prasad belongs to a distinctly different and unconventional species of doctors. He speaks sparingly and does not even display his qualifications or merits, but his innumerable published writings (he calls them ‘scribblings’ though they are ‘pearls of wisdom and knowledge’, sprinkled with a bit of humour and sarcasm) which received wide acclaim talk eloquently for him. The ‘PAY WHAT YOU CAN’ Clinic where services are available for which one may pay whatever one can is a facility run by Dr. Prasad for a very long time which could be a world record. Dr. Prasad is called a “god” by his patients, and many of them named their children after his name “Prasad” -- that is the height of recognition of goodness of a human being.." 

 Service to Humanity is service to God;             Kindness costs nothing

********************************

                                                            

A short list of some of the published articles                                           VEGA%20portrait%20F%20Final%20.png

authored / co-authored by   Versha Rajeev:



 

1.     Fear and COVID-19 – HEALTH,  Vol. 98,  No. 11,  pp. 13 -14,  2020

2.     Antiseptics, Disinfectants and COVID-19 – THE ANTISEPTIC,  Vol. 117,

               No. 11,  pp. 26 – 28,  2020

3.     Tea and COVID-19 – HEALTH,  Vol. 98,  No. 10, pp. 4 – 6,  2020

4.     The Conundrum of COVID-19 Vaccines – THE ANTISEPTIC,    Vol.  118,                                       No. 1,  2021

 

================================================================

 

Some writings, presentations, papers and comments related to TUBERCULOSIS  by  Dr. T. Rama Prasad:

 

 1.      https://www.thehindu.com/opinion/open-page/a-bad-patch/article31069356.ece 

 2.       Five years Plans and TB Control Programme (Special Article) - 

          The Hindu,  Vol.101, No. 275,  November 24,1978

 3.       How effective is the TB control programme ?  (Special Article) -  

          The Hindu,  Vol.100,  No. 274,  p.8,  1977.

4.   https://drtramaprasad.blogspot.com/2017/04/yellow-nail syndrome_28.html

5.      https://drtramaprasad.blogspot.com/2017/04/tuberculosis-in-india_29.html

 6.      Rama Prasad, T.,  COVID and Tuberculosis.  The Antiseptic, 2021  December; 

                               Vol.   118; No.12; P: 11-17;  Indexed in IndMED --  www.antiseptic.in

 7.       https://drtramaprasad.blogspot.com/2017/04/tb-and-covid.html

 8.       Drug Resistance in Tuberculosis  -  Journal of the Indian Medical 

          Association,  Vol.  64, pp. 264-267,  1975.

 9.      Childhood Tuberculosis - Part I - The Antiseptic, Vol. 76, pp. 449-504,1979

10.      Childhood Tuberculosis - Part II - The Antiseptic, Vol. 76.  pp. 567-574, 1979

11.    Short-course Chemotherapy - The recent Advances in the Treatment

           of Respiratory Tuberculosis - Current Medical Practice, Vol.24,

           pp. 41-46, 1980.

12.    Drugs in the treatment of Tuberculosis - The Antiseptic

          Vol. 75,  p.678, 1978

13.    Chemotherapy of Tuberculosis - The Antiseptic,  Vol. 76,  p.248,  1979.

14.    Streptomycin in Tuberculosis - The Antiseptic,  Vol. 76,  p.516,  1979.

 

15.   National Tuberculosis Control Programme -  views presented,  

        on invitation  by theTuberculosis Association of India,  at the 32nd 

        National Conference on  Tuberculosis and Chest Diseases,  1977.

16.   Correlation between Geomagnetic Activity and Haemoptysis -

        paper  presented at the II Tamil Nadu State Conference on Tuberculosis 

        &  Chest Diseases,  1980.

 17.   RADIO TALK  All India Radio, ‘The Threat of the Bacillus’ by  Dr. T. Rama Prasad,             ,        June 28, 1996

 

18.    Elimination of Tuberculosis by 2025  --  The Antiseptic,  2026

 

The following is a list of some of my 'scribblings', including a few from the 28 articles on COVID published in a monthly medical journal in 30 months (a world record).   To open them, click on any of the titles.  --  T. Rama Prasad

Blog Archive

▼  2024 (2)

·       ▼  May (2)

o   CHARITY -- a perspective, a reality check

o   THE NOBLE PROFESSION

·   ▼  2017 (115)

o   ▼  March (1)

§  COVID MEDICAL LITERATURE

o   ▼  April (112)

§  OREIKLE

§  DEEPAAVALI

§  Science and Nonsense about COVID

§  AMC BATCH 1959 (revised)

§  Nurses Day 2017

§  FOOD, EXERCISE and SLEEP

§  OMICRON -- a paper tiger ?

§  World TB Day: TB and COVID

§  INDIAN ENGLISH

§  MY QUOTES & JOKES

§  COVID, SCHOOLS & CHILDREN

§  LOCKDOWN MEDICINE

§  Death Penalty

§  COVID CROCODILES

§  Number 13

§  WORLD CANCER DAY ..February 4, 2017

§  CORONA VARIANTS

§  PERUNDURAI is the GEM

§  Covishield or Covaxin ?

§  GRADUATION DAY -- 2018, Perundurai Medical Col...

§  "AHIMSA"

§  STAFF & STUDENTS. -- photos

§  SINGAPORE

§  BRINGING UP CHILDREN

§  HAPPY 2018

§  Dr. T. Rama Prasad

§  OMICRON

§  QUOTES

§  POLLUTION, Disease and Deepaavali

§  CESAREAN DELIVERY

§  DOCTORS' HANDWRITING MATTERS

§  RAJYALAKSHMI and SPB

§  PONGAL FESTIVAL

§  To live in INDIA or ABROAD ?

§  THE HINDU newspaper & ME

§  KMCH

§  FISHES

§  RICHNESS and HAPPINESS

§  YELLOW NAIL SYNDROME

§  BIRDS and DANGEROUS DRUGS

§  ABDUL KALAM

§  SUNDAY LUNCH ... Dec 3, 2017

§  VINAYAKA chathurdhi 2017

§  BAHUBALI

§  COMPLEXION

§  DENGUE, ZIKA and MOSQUITO

§  FOOLED TO BELIEVE

§  OBESITY and DIABETES

§  TUBERCULOSIS in India

§  MY ART

§  CIVIC SENSE & MANNERS

§  SMILE and STRESS

§  CANCER

§  DOGS

§  GOD-MEN

§  CODUP

§  LOCKDOWN MEDICINE -- too toxic ?

§  GOD, RELIGION & UNIVERSE

§  CORONA and CHARLES DARWIN

§  YOGA

§  HCQ, IVERMECTIN, CORONAVIRUS and FRAUDS

§  INDIAN SUPERBUG

§  SWINE FLU -- A (H1 N1) influenza

§  NIPAH & ZIKA viruses

§  SOPHISTICATED CHEATING

§  PERUNDURAI MEDICAL COLLEGE & SANATORIUM campus

§  RAJYALAKSHMI RAMAPRASAD and PLANTS

§  MY REAL AWARDS

§  GIRL CHILD : GOLDEN CHILD ; WOMEN POWER

§  ALLERGY, ASTHMA, COPD and ILD

§  TEST-TUBE PUPPIES

§  CREATE / KILL a baby

§  ONAM 2017

§  OPEN AIR DEFECATION

§  DRESS SENSE

§  SEXUAL HARASSMENT

§  RAPE

§  THE CHANGING WORLD

§  MARRIAGE and MATING

§  TEA, COFFEE and COMMERCE

§  DEVALUED DEGREES

§  SCHOOL and NEET

§  INCREDIBLE INDIA !

§  MARKETING TRICKS & INNOVATIONS

§  INTERNET EFFECT

§  RURAL ARE THE REAL

§  MEDICINE IN RURAL INDIA

§  RUN ON MONEY

§  MEDICAL CONFERENCES

§  Dr. Peon, PhD

§  MODERN MEDICINE -- the Good, the Bad and th...

§  YOU ARE NOT OLD

§  RAJYALAKSHMI & International Women's Day 2025 & ...

§  SHIVA, KRISHNA, Ramanuja & Ramanujan

§  BETTER HALF

§  OUR LOVE STORY & good old days

§  'PAY WHAT YOU CAN' Clinic

§  ABOUT ME and MY SCRIBBLINGS

o   ▼  May (2)

§  FICUS trees and GODS

§  Post-Omicron Peregrination

·   ▼  2019 (1)

o   ▼  January (1)

§  AMC batch 1959

·   ▼  2020 (3)

o   ▼  February (1)

§  OVER-HEALTHCARE

o   ▼  April (1)

§  RAJYALAKSHMI RAMAPRASAD and RADIOGRAM

o   ▼  June (1)

§  CORONAVIRUS COVID-19 (SARS-CoV-2)

·   ▼  2022 (1)

o   ▼  October (1)

§  VCW Rajyalakshmi, BLOG

·   ▼  2023 (25)

o   ▼  January (23)

§  TRUMPOLITICS

§  RIGHT or WRONG ???

§  MONKEYPOX (Mpox)

§  FASTING

§  TUBERCULOSIS -- drug-resistant

§  LONG and SHORT of COVID

§  MENTAL HEALTH

§  VERSHA, alias Vega

§  STRESS and PSYCHOSIS

§  HEART

§  ZERO COVID

§  INDIAN IMMUNITY, BCG and COVID

§  WOW !!!

§  STRANGE EVOLUTION

§  MANGO, BANANA & JACKFRUIT

§  ARTIFICIAL INTELLIGENCE

§  COVID vaccines -- Safe or Unsafe ?

§  The Unique Academy

§  COVID -- ANTISEPTIC JOURNAL

§   SNAKES  (Reptiles) MYSTERIOUS  REPTILES

§  SNAKES -- Reptiles

§  RAJYALAKSHMI's 100 POEMS

§  MEDICAL SYSTEMS

o   ▼  August (1)

§  RAMAYAAN

o   ▼  October (1)

§  NEET SAGA

An anecdote about  “GORU”

 

During my childhood, one of my schoolmates had huge nails.  Her name was Gowri.  We nicknamed her as ‘Goru’ (‘goru’ in Telugu means nail of a finger or toe ).  They used to say that her huge nails caused a problem in her heart.  It might be a case of ‘Digital Clubbing’ (abnormal nails present in some ‘Congenital Heart Diseases’).  After one summer vacation, ‘Goru’ didn’t come back to the school.  It was learnt that she died due to the nail / heart problem, and that treatment could not be availed as they didn’t have money to pay for it. 

 

Perhaps, this incident prompted me to look at everyone’s nails from that time which might have led me to report the first case from India of ‘Yellow Nail Syndrome (YNS)’  in 1980 (published in an American journal, CHEST) and the first case in the world of ‘Yellow nails & Covid’ in 2023, published in an Indian journal, THE ANTISEPTIC - https://drtramaprasad.blogspot.com/2017/04/yellow-nail syndrome_28.html

 

And perhaps, the preventable death of ‘Goru’ due to the inability to pay for the treatment motivated me to start my ‘PAY WHAT YOU CAN’ Clinic half-a-century ago where patients may pay whatever they can. No fixed fee http://drtramaprasad.blogspot.com/2017/06/pay-what-you-can-clinic.html ).   The credit for these case reports on YNS and the starting of my ‘Pay What You Can’ Clinic should go to ‘Goru’.  Thanks to “Goru”.

 

                                                        --     T. Rama Prasad

 





 

 

This is not an ad,  it’s about an odd service.

 

Dr. T. Rama Prasad’s    PAY  WHAT  YOU  CAN’  Clinic

“Thena  thyakthena  bhoojithaha”– Ishopanishad

   ( Translated by  Prof. B.M. Hegde  as: “Rejoice  in  giving.”)

 

          True to this quote, I have been rejoicing at what little I could give.  Defying stereotypes, this clinic has been in existence for a very long time, sans glitz, blitz, ads, microphones, speeches and noise.  As a matter of my policy, publicity is shunned.  The reason is simple.  Good work needs no noise and nonsense.  My ‘SCRIBBLINGS’ on related topics may be accessed at:  http://drtramaprasad.blogspot.com

 



 

 Yes, ‘PAY WHAT YOU CAN & WISH’, as the consultation fee.  It is the patient’s choice.  It may even be zero.  The patient may pay (donate) any amount.   The money may just be put into the ‘hundi’ box,  or remitted   through the ‘Google Pay/UPI’ QR code.  And the money thus received is used for charity to help the needy, the poor, and the less fortunate.  If interested to know more about this facility, go to: http://drtramaprasad.blogspot.com/2017/06/pay-what-you-can-clinic.html .  And, even if you are not a patient, if you wish, you may also 'contribute whatever you can'  in the same way.

 

   "We need not run after money.  If we are meritorious and compassionate, money would run after us, and it eludes us if we run after it.”      --  T. Rama Prasad 

 

            “Richness is not having lots of money.  It is the feeling that one has enough of it.   Contentment sans comparison is what makes one really rich.”     --  T. Rama Prasad.    

  

                                                                             

                            Facebook: T Rama Prasad   Twitter: @DrRamaprasadt     Telegram :  Dr T Rama Prasad

                             




Consult your local doctor before rushing to me.

Most ailments can be cured at local level.

 

                                         For APPOINTMENT with Dr. T. Rama Prasad,  contact :  98427 20393

 

To know a little about the TB sanatorium & the Perundurai Medical College, click on  https://drtramaprasad.blogspot.com/2017/04/perundurai-medical-college-sanatorium_29.html  

 

Left to right:  

Dr. T. Rama Prasad, Former Medical Superintendent (Special) of RT Sanatorium & Perundurai Medical College, (2) Dr. S. Prabhakar, Erode District Collector, (3) Thiru Thoppu N.D. Venkatachalam, Ex Minister & Perundurai MLA, (4) Dr. S. Geethalakshmi, Vice-Chancellor of the Tamil Nadu Dr. MGR Medical University, (5) Prof. Dr. M. Rajendran, Dean of the IRT Perundurai Medical College, (6) Thiru V. Shanmugan, Chairman of The Nandha Educational Trust. 

From a   BLOG  ARTICLE  in  :  http://drtramaprasad.blogspot.com  




On December 30, 2019 when I attended a function at the college.


To know more about this medical college and the sanatorium,  Click on : https://drtramaprasad.blogspot.com/2017/04/perundurai-medical-college-sanatorium_29.html



 The first outbreak of COVID in the world was reported in China on the very next day (31.12.2019) of taking the above photo on 30.12.2019 !!!

This sanatorium (Ramalingam Tuberculosis Sanatorium) was a premier institution in India with 350 beds for TB patients (charge-free & chargeable luxury cottages, spread over a sprawling vegetation-rich-pollution-free-326-acre-hinterland, with selubrious climate, where the in-patients used to stay for months).  Later, a medical college (Perundurai Medical College) was established in the sanatorium campus, around the year 2000.  With the introduction of domiciliary (home) TB treatment & the establishment of the medical college in the campus, the sanatorium gradually faded away, after I retired from the post there.




At the END of the YEAR (25-12-2025),  the Indian Council of Medical Research – National Institute for Research in Tuberculosis (ICMR – NIRT) and Women’s Collective Forum, in their new report released on 25.12.2025, recommended making TB-related content mandatory in UG & PG medical courses and urged active participation of medical colleges in the National TB Elimination Programme (NTEP).  They have also recommended creation of dedicated beds at various levels of medical care, citing that 26.81 lakh TB cases were diagnosed in India in 2024 .

 

Hallelujah !   2026 sans TB  !   No ?




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2 comments:

  1. I really appreciate  DR AKHIGBE,my name is LAURIE HUGHES . I will never stop testifying DR AKHIGBE , Happiness is all i see now I never thought that I will be cured from HIV virus again. DR AKHIGBE did it for me I have been suffering from a deadly disease (HIV) for the past 2 years now, I had spent a lot of money going from one place to another, from churches to churches, hospitals have been my home every day residence. Constant checks up have been my hobby not until this faithful day,  I saw a testimony on how DR AKHIGBE helped someone in curing his HIV disease in internet quickly I copied his email which is drrealakhigbe@gmail.com just to give him a test I spoke to him, he asked me to do some certain things which I did, he told me that he is going to provide the herbal cure to me, which he did, then he asked me to go for medical checkup after some days, after using the herbal cure and i did, behold I was free from the deadly disease,till now no HIV in me again he only asked me to post the testimony through the whole world, faithfully am doing it now,all the testimony of DR AKHIGBE is true  please BROTHER and SISTER, MOTHER and FATHER he is great, I owe him in return. if you are having a similar problem just email him on drrealakhigbe@gmail.com or you can whats App his mobile number on +2348142454860  He can also cure these diseases like HIV and AIDS HERPES,DIABETICS,CANCER, HEPATITIS A&B,CHRONIC DISEASES, ASTHMA, HEART DISEASES, EXTERNAL INFECTION, EPILEPSY, STROKE, MULTIPLE SCLEROSIS, NAUSEA,VOMITING OR DIARRHEA,PARKINSON DISEASE,INFLUENZA,. COMMON COLD, AUTOIMMUNE DISORDER, MENINGITIS, LUPUS,ECZEMA,BACK PAIN, JOINT SCHIZOPHRENIA , TUBERCULOSIS, PAIN.LOWER RESPIRATORY INFECTION. .ETC .please email drrealakhigbe@gmail.com    or whats APP him  ..+2348142454860  he is a real good and honest man.  
    website...  https:drrealakhigbe.weebly.com

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  2. My name is hoover, my 18 year old daughter, Tricia was diagnosed with herpes 3 years ago. Since then, we have moved from one hospital to another. We tried all kinds of pills, but every effort to get rid of the virus was futile. The bubbles continued to reappear after a few months. My daughter was using 200mg acyclovir pills. 2 tablets every 6 hours and 15g of fusitin cream. and H5 POT. Permanganate with water to be applied twice a day, but all still do not show results. So, I was on the internet a few months ago, to look for other ways to save my only son. Only then did I come across a comment about the herbal treatment of Dr Imoloa and decided to give it a try. I contacted him and he prepared some herbs and sent them, along with guidance on how to use them via the DHL courier service. my daughter used it as directed by dr imoloa and in less than 14 days, my daughter recovered her health. You should contact dr imoloa today directly at his email address for any type of health problem; lupus disease, mouth ulcer, mouth cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, HIV / AIDS, Huntington's disease, back acne, chronic kidney failure, addison's disease, chronic pain, Crohn's pain, cystic fibrosis, fibromyalgia, inflammatory Bowel disease, fungal nail disease, Lyme disease, Celia disease, Lymphoma, Major depression, Malignant melanoma, Mania, Melorheostosis, Meniere's disease, Mucopolysaccharidosis, Multiple sclerosis, Muscular dystrophy, Rheumatoid arthritis Alzheimer's disease, parkinson's disease, vaginal cancer, epilepsy Anxiety Disorders, Autoimmune Disease, Back Pain, Back Sprain, Bipolar Disorder, Brain Tumor, Malignant, Bruxism, Bulimia, Cervical Disc Disease, Cardiovascular Disease, Neoplasms , chronic respiratory disease, mental and behavioral disorder, Cystic Fibrosis, Hypertension, Diabetes, Asthma, Autoimmune inflammatory media arthritis ed. chronic kidney disease, inflammatory joint disease, impotence, alcohol spectrum feta, dysthymic disorder, eczema, tuberculosis, chronic fatigue syndrome, constipation, inflammatory bowel disease. and many more; contact him at drimolaherbalmademedicine@gmail.com./ also with whatssap- + 2347081986098.

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